To analyze the impact of IKK2 inhibitor VIII (HY-13060, Medchem Categorical, Monmouth Junction, NJ) on OA improvement, MLI surgeries were being carried out in twelve-week-previous C57BL/six WT mice. The mice have been injected with IKK2 inhibitor VIII (two?mg/kg, IP) every single alternate working day for 5 months. OARSI scoring was done by blinded

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